Which Nootropics Actually Work: Our Naturally Powerful Picks

There is a wide variety of supplements on the markets these days that are categorized as nootropics, but this type of variety can make it difficult to determine which nootropics actually work and which ones donā€™t.

Basically, nootropics work by altering the hormones, enzymes, and neurochemicals in the brain, in order to increase cognitive function, memory, mental alertness, and mental focus.

But if youā€™re new to the world of nootropics and want to find a product that will work for you, what should you look for and what types of results can you really expect?

Which nootropics actually work?

There are many all-natural nootropics that work and can provide impressive results, depending on why the user needs nootropics.

But many of the all-natural nootropic supplements and stacks can take significantly longer to work, compared to the type of nootropics known as racetams.

The most effective natural nootropics include:

  • L-Theanine
  • Caffeine
  • Bacopa Monnieri
  • Creatine

While there are many more types of nootropics to choose from, these all-natural options can provide many of the benefits youā€™re looking for if you want to improve mental focus and promote brain health and boost brainpower.

There are many nootropics to choose from, and while these all-natural options may not be quite as powerful as some types of over the counter products, they have an excellent reputation for promoting increased mental clarity, fighting age-related dementia, and can provide a number of other health benefits that make them worth a second and third look.

A Mental Boost You Wonā€™t Forget

According to scientists, nootropics just may be the key to unlocking the mindā€™s full potential. But how can you tell whether or not a particular brand of nootropics can work?

What makes one type of nootropics better than another?

Is it really possible to take a pill and enjoy improved mental clarity, brainpower, memory, and focus, within minutes?

Do some types of nootropics work better, more efficiently than others?

Nootropics are designed to change certain chemical levels in the brain and how these chemicals interact.

Neurotransmitters are responsible for pain, appetite, pleasure, motivation, memory, mood, learning, anxiety, and focus, and the brain is full of them.

But considering how complex brain chemistry is, science today is only just now beginning to understand how neurotransmitters work and why.[1]http://www.minddisorders.com/Kau-Nu/Neurotransmitters.html

What science does know thus far is that itā€™s possible to change the number of neurotransmitters in the brain and that doing so can have a major impact on how we feel, think, and act.

Neurotransmitters in Motion

Neurotransmitters in Motion

Each person has their own unique brain chemistry, meaning they produce different levels of certain types of neurotransmitters. Because of this, not every person will benefit from the same type of nootropics.

Essentially, neurotransmitters are information carriers. Based on the type of information thatā€™s being transmitted, the receiving neuron can respond in several ways.

Ultimately, the neuron will further transmit a certain message to other brain cells until the right cognitive outcome is achieved.

Below is a list of the most relevant types of neurotransmitters:

  • Serotonin: Relaxation
  • Acetylcholine: Cognition, learning, memory
  • Dopamine: Motivation and mood
  • Epinephrine: Intense energy
  • Norepinephrine: Focus
  • GABA: Also known as gamma-aminobutyric, this neurotransmitter is responsible for calmness and sedation.

Ideally, a person should have a healthy reserve of each of these important neurotransmitters. But an imbalance in levels of neurotransmitters or issues with the uptake, release, or synthesis of neurotransmitters can have a major impact on brain function, resulting in a disruption in memory, cognitive function, emotions, and more.

This is where nootropics come in. The best nootropics can work to optimize these neurotransmitters, working to:

  • Prevent breakdown of neurotransmitters
  • Promote synthesis
  • Supply brain chemical precursors
  • Improve the sensitivity of receptors

Certain types of nootropics can also engage specific neurotransmitter pathways.

Brain Health and Improved Circulation

Improved brain circulation will not only involve promoting blood flow in order to deliver important compounds, itā€™s also a matter of ridding the brain of harmful neurotoxins (a poison that acts on the nervous system) found in neuronal tissue.

This type of balance is essential in terms of age-related decreases in cognition. Impaired circulation in the brain can allow plaque to grow, which can hinder the neural pathways in the brain, causing a common form of dementia called Alzheimerā€™s disease.

Unfortunately, as we age, circulation in the brain tends to decrease. Additionally, a decrease in cerebrovascular function is commonly linked to age-related cognitive problems and brain degeneration.

How Effective is L-Theanine?

L-Theanine, one of the most effective nootropics, is able to significantly increase brain waves, targeting the alpha brain waves. Doing so can improve important cognitive functions, mental clarity, and focus.[2]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080935/

Most nootropics will contain some level of L-theanine, which can naturally be found in tea. This chemical compound is often associated with relaxation, cognition, and anxiety reduction.

Itā€™s a glutamic acid and an amino acid and itā€™s considered a safe psychoactive substance. It can also be combined with caffeine since both L-theanine and caffeine work to increase mental endurance, memory, and reaction time.

Caffeine – The Most Popular Type of Nootropics

The most common type of nootropics has to be caffeine. Itā€™s been used for hundreds of years and, in lower doses, can provide a safe way to boost brain function, focus, and mental clarity.

Some studies even claim that people who normally consume coffee have a much lower chance of developing dementia and Parkinsonā€™s disease, in addition to other types of memory-related conditions.[3]https://www.parkinson.org/blog/science-news/coffee-and-parkinsons-protection-in-the-making

While coffee and other products that contain caffeine can provide a significant boost in mental alertness, almost instantly, the effects of caffeine tend to be short-lived.

However, if youā€™ve ever tried a caffeinated drink, thatā€™s proof right there that some nootropics really do work.

Bacopa Monnieri – A Magical Herb

Bacopa Monnieri is an herb thatā€™s native to India and is a type of nootropic thatā€™s commonly used for memory enhancement purposes.

It can also be used as a natural mood elevator, or to treat epilepsy and asthma. A study on the effects of Bacopa Monnieri showed that consistent use can decrease age-related dementia while improving nerve pulse transmission.[4]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669844/

Nerve pulse transmission is responsible for improved alertness and mental focus. Considered one of the most effective and safest mood enhancer nootropics around, itā€™s also one that comes with the least side effects.[5]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075615/

Many of the leading nootropics supplements will contain a high percentage of Bacopa Monnieri.

Creatine – A Powerful Nootropic

Produced in the kidneys, with a process thatā€™s completed in the liver, creatine is then stored in the muscles and tissues in the brain. It works to support both physical and mental strength and is commonly used by athletes to increase muscle tissue recovery and reduce fatigue.

Aside from helping the body to recover at a faster rate, it can also work to enhance mental and cognitive functions.

Some studies suggest that it can help with the treatment of cognitive decline in people when itā€™s used in combination with other types of therapy.

It can also help to treat people with a Huntingtonā€™s or Parkinsonā€™s disease diagnosis. There are some mild side effects associated with creatine use. In fact, an overdose of creatine can cause anxiety, weight gain, and gastrointestinal issues.

A Nootropic that can Prevent Serious Damage to Brain Cells

Alpha-lipoic acid has antioxidant properties, although itā€™s a type of vitamin-like chemical that is found in potatoes, liver, kidneys, yeast, spinach, and broccoli.[6]https://www.ncbi.nlm.nih.gov/books/NBK564301/

This chemical is often prescribed to people who have complications from diabetes such as nerve-related pain since it helps to prevent further nerve damage and can also improve neuron function.

Itā€™s also considered one of the best all-natural memory-boosting compounds around. Alpha-lipoic acid is able to pass through the blood-brain barrier easily and itā€™s also known to protect the nerve tissues found in the brain.[7]https://pubmed.ncbi.nlm.nih.gov/8958163/

Some studies suggest that this acid plays an important role in stroke prevention because it can decrease the number of free radicals found in the body. Itā€™s also a powerhouse when it comes to increasing acetylcholine production.

Alpha-lipoic acid can potentially restore normal vitamin E and C levels in the body. Its antioxidant properties can protect the brain cells from serious damage in the event of an injury and can also ensure that the brain functions properly in the event of an internal or external brain injury.[8]https://vitagene.com/blog/what-is-alpha-lipoic-acid/

Nootropics and Safety

Are nootropics bad for you? No, in fact, most types of nootropics are considered safe, when used correctly.

Some types of nootropics are all-natural and sold over the counter, while others will require a prescription, depending on the country you live in.

These types of nootropics may require a subscription because they have a reputation for being abused by the user. Nootropics, in general, are very powerful brain-boosting drugs that should be taken accordingly.

Because everyoneā€™s brain chemistry is so different, thereā€™s no guarantee that you wonā€™t experience an adverse reaction when you try nootropics.

Fortunately, you can contact your doctor or speak with a pharmacist to determine whether or not a drug interaction is likely, based on any current medications youā€™re taking. You can also speak with your doctor if you have a certain underlying health condition that would make you a poor candidate for nootropics use.

Related Questions

Do Nootropics Have Side Effects?

Yes, some do. The most common reported side effect from nootropics used is headaches. However, there have also been reports of dizziness, nausea, insomnia, and restlessness. The potential for side effects can vary from person to person.

As an example, some nootropics that contain caffeine can cause nausea or headaches in a person thatā€™s very sensitive to caffeine but will cause no side effects in someone who normally drinks coffee.

What Do Nootropics Do?

Nootropics are often referred to as smart drugs and contain chemicals and compounds that are designed to improve mental focus, alertness, brain power, and cognition.

Some types of nootropics are all-natural, while others are synthetic (lab-made). Some of these supplements are not designed to be taken on a daily basis, and instead should only be taken on occasion when a boost in brain power is needed.

Is Caffeine a Nootropic?

Yes. Caffeine is actually considered the most commonly used type of psychoactive drug the world over. Itā€™s also categorized as a type of nootropic because it can help to improve many brain functions including mood elevation, improved memory, increased alertness, and improved reaction time.

In normal doses, caffeine is very safe to use. However, in large doses, it can cause unwanted side effects such as increased heart rate, heart palpitations, heart attack, anxiety, upset stomach, and gastrointestinal distress.

How Long Do Nootropics Take to Work

Some types of nootropics can take as long as one to eight weeks to take effect, while others will take as little as twenty to thirty minutes. Some types of nootropics are not designed for daily use, while others (typically all-natural nootropics) should be taken over a long period of time in order to achieve the compounding effect, a point in which youā€™ll feel the full effects.

Make sure you carefully read the nootropicā€™s dosing instructions in order to learn whether or not the product youā€™ve purchased is designed for daily use.

Final Thoughts

Which nootropics actually work? L-Theanine, caffeine, Bacopa Monnieri, and creatine are just some of the leading all-natural nootropics on the market.

Theyā€™re commonly found in high-quality stacks and can provide natural energy, a boost in mental alertness and clarity, and other benefits that can give your brain a boost in power.

So, yes, there are nootropics out there that really work. However, considering everyoneā€™s brain chemistry is different, certain types of nootropics will not work for everyone.

It will be all about experimenting until you find the perfect supplement or stack that can give you the type of brain power youā€™re searching for.


Taylor Bates

Taylor is a neurohacking expert who has been in the world of nootropics since it gained popularity almost 10 years ago. He overcame his ADD, procrastination and lack of focus with nootropics. Now, he is sharing his knowledge and experience here at NootroPicks.com to help others navigate the world of cognitive enhancement.
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Which Nootropics Actually Work: Our Naturally Powerful Picks
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Which Nootropics Actually Work: Our Naturally Powerful Picks
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Learn about the leading types of nootropics, which products offer the best results, and how you can take nootropics for an instant boost in brain power.
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